It’s National Viagra Day (and it has a new side effect)

[Ali Gator]

A recent study has confirmed the findings of earlier research which indicates people who regularly take erectile dysfunction medication—particularly Viagra—have a lower risk of developing Alzheimer’s Disease.

Why the drugs appear to lessen the occurrence of Alzheimer’s is unknown. However, one theory is that the medication increases blood flow to all parts of the body, including the brain.

The results of the latest research appeared in Neurology. Scientists looked at the health records of 269,725 men in the UK. Aged over 40, the average age was 59.

It’s National Viagra Day & a new study has just found an unexpected side effect of the little blue pill

WWW.QUEERTY.COM

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And why exactly does World Viagra Day fall on March 27...

 

[Monarchy79]

This is great news…. 
No one wants to be walking around with a hard dick, and then not remember what to actually do with it….. 

[topunderachiever]

I'm curious.  What percentage of men (in the US) over the age of 60 do you think use ED meds regularly for their sexual encounters?  

[Monarchy79]

3 hours ago, topunderachiever said:

I'm curious.  What percentage of men (in the US) over the age of 60 do you think use ED meds regularly for their sexual encounters?  

This is a really good question, as I personally know of two guys who use it, they a both under 50, and use it for recreational purposes.

 

[Thomas_Belgium]

22 hours ago, topunderachiever said:

I'm curious.  What percentage of men (in the US) over the age of 60 do you think use ED meds regularly for their sexual encounters?  

According to these numbers:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540144/

and if my calculations are correct, it's about twelve percent.

[marylander1940]

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[Ali Gator]

I'm convinced many young providers use it - many.  I don't care how fit and sexually active you are in your 20s and 30s - how can they maintain an erection all day / night with different clients when they have a full schedule ? Or if they are not sexually attracted to their client ? 

[Rudynate]

On 3/28/2024 at 10:01 AM, Ali Gator said:

A recent study has confirmed the findings of earlier research which indicates people who regularly take erectile dysfunction medication—particularly Viagra—have a lower risk of developing Alzheimer’s Disease.

Why the drugs appear to lessen the occurrence of Alzheimer’s is unknown. However, one theory is that the medication increases blood flow to all parts of the body, including the brain.

The results of the latest research appeared in Neurology. Scientists looked at the health records of 269,725 men in the UK. Aged over 40, the average age was 59.

It’s National Viagra Day & a new study has just found an unexpected side effect of the little blue pill

WWW.QUEERTY.COM

---

And why exactly does World Viagra Day fall on March 27...

 

I read long ago that they prevent endothelic dysfunction (the lining of your blood vessels).  I took a 5 mg dose of cialis for years, but it started to lower my blood pressure too much so I had to stop.

[Thomas_Belgium]

43 minutes ago, Rudynate said:

... I took a 5 mg dose of cialis for years, but it started to lower my blood pressure too much so I had to stop.

 

With a pill cutter I can cut a 2,5 mg in half & sometimes I skip a day because it works 48 hours.

[Ali Gator]

2 hours ago, Thomas_Belgium said:

 

With a pill cutter I can cut a 2,5 mg in half & sometimes I skip a day because it works 48 hours.

Pics please...let's see how well a half pill works. 😜

[Rudynate]

12 hours ago, Thomas_Belgium said:

 

With a pill cutter I can cut a 2,5 mg in half & sometimes I skip a day because it works 48 hours.

2.5 might be just right.

[Thomas_Belgium]

20 hours ago, Ali Gator said:

Pics please...let's see how well a half pill works. 😜

 

Pics don't prove how hard it is...

[Ali Gator]

1 hour ago, Thomas_Belgium said:

 

Pics don't prove how hard it is...

Ok....videos please. 

[Thomas_Belgium]

The half pill works very well for me but not when a camera rolling, sorry.

[mtaabq]

I am 61 and overweight. I use the V occasionally (perhaps once a month) when my F-Buddy wants me to top him and his husband wants to watch. I am continually amazed and delighted at how thick my dick gets on the V. And, I seem to last a bit longer, too. Remember, guys, do not use poppers if you take ED meds. 

[+ Just966]

Where are people getting generic viagra or cialis from for a decent price these days. I am looking to order from Canada. Thanks!

[BuffaloKyle]

3 minutes ago, Just966 said:

Where are people getting generic viagra or cialis from for a decent price these days. I am looking to order from Canada. Thanks!

I can't wait for the day when it's available OTC. I've tried it and liked it but I only have sex though when I hire pretty much. So I don't need an ongoing prescription. Just would be nice to go pick up a small pack when I'm in the hiring mood.

[+ purplekow]

If you can get the generic Sildenifil in 20 mg tabs, then you can adjust your dose to your needs.  I usually use 40 mg occasionally none at all and 20 or 60 with equal frequency.  The 60 gets me very hard but after my partner has left I frequently get another erection and am left holding the bag (and the dick)

[+ Just966]

7 minutes ago, purplekow said:

If you can get the generic Sildenifil in 20 mg tabs, then you can adjust your dose to your needs.  I usually use 40 mg occasionally none at all and 20 or 60 with equal frequency.  The 60 gets me very hard but after my partner has left I frequently get another erection and am left holding the bag (and the dick)

And that is an issue, why?😊

[mtaabq]

8 hours ago, Just966 said:

Where are people getting generic viagra or cialis from for a decent price these days. I am looking to order from Canada. Thanks!

I got mine in Mexico whilst on a cruise. I paid four US$ per pill. Minimum quantity was ten. The Farmacias are everywhere in port. I’m cruising again this fall and planning to stock up. 

[+ Just966]

I had ordered online in the past but some places have closed so not sure of best option now. 

[KeepItReal]

36 minutes ago, Just966 said:

I had ordered online in the past but some places have closed so not sure of best option now. 

BlewChew is very accessible and fairly cheap. Ro and Hims are also options, but more expensive.  Be careful ordering online - quality can be a real issue.  

https://www.fda.gov/drugs/drug-supply-chain-integrity/internet-pharmacy-warning-letters

[+ Just966]

19 minutes ago, KeepItReal said:

BlewChew is very accessible and fairly cheap. Ro and Hims are also options, but more expensive.  Be careful ordering online - quality can be a real issue.  

https://www.fda.gov/drugs/drug-supply-chain-integrity/internet-pharmacy-warning-letters

Thanks! That's a long list of no go online pharmacies😬. Does anyone have one that they use and feel good about? I have ordered from alldaypharmacy in past but  think I couldn't last time. 

[SirBillybob]

I would interpret with reservation as it doesn’t pass the smell test if you drill down further, including into the reams of supplementary data appended. The results don’t satisfy standard assumptions of causality.

For the first 14 years (circa 2000-13) the Alzheimer’s (AD) number-at-risk ratio based on subgroup denominators was 3:1, loaded for PDE5i use, and there was an apparent scramble to equalize the ratio over the final 3-4 years to an eventual number-at-risk ratio that landed at 1.2:1 AFTER the Kaplan-Meier incidence curves trended to merging, thus having shown at that 14 year point no difference in Alzheimer’s incidence between PDE5i users and non-users. Hence the average follow-up period was about 6 years for PDE5i users, twice the period length compared to that of non-users because the majority of non-users with ED in the database were chased down closer to the end of the retrospective study period. 

Moreover, the average age of non-users was 78 at date of AD diagnosis, 2 years older than that of PDE5i users at their date of diagnosis, so PDE5i users were diagnosed at a younger age. However, one would not be inclined to say PDE5i use predisposed to younger AD onset UNLESS wanting to put forward a finding as specious as the actual biased published results.

Non-users diagnosed with AD had higher rates of comorbidities (on all 18 conditions measured, and with comorbidity prevalence differentials much greater than that of AD incidence comparing the subgroups!) [comorbidities are associated with AD] as well as higher rates of illness medication treatments compared to PDE5i users. They were older and sicker and these factors alone could explain a higher rate of Alzheimer’s Disease using the person-years denominator over the shorter period of time assessed for that subgroup. For greater than mid-70’s age range the AD incidence curve begins to rise more steeply, for example age 78.5 compared to age 76.5 within the general population. Based on age standard deviation values depicted in the study herein reviewed, 68% of PDE5i users at time of AD diagnosis were age 69.5-83.7 while 68% of non-users were age 71.6-85.4

Since PDE5i’s are widely used for ED the reality that uptake would be nil in spite of ED diagnosis supports the notion that the importance and pursuit of sexual function may have been secondary for them in the context of worse health overall. More meds, more drug interaction, more onerous dosage adjustment considerations, less incentivizing for PDE5i uptake. These factors suggest the possibility of reverse causation; an association between the prodomal stage of AD and PDE5i non-prescribing as opposed to causative directionality where no uptake predicts AD and uptake is protective against AD. 

In sum, there would be no more reason to conclude PDE5i uptake confers Alzheimer’s risk reduction than to assert it lowers incidence of the 18 comorbidities tracked. The non-users had higher vulnerabilities to cognitive decline but never having popped Viagra or other PDE5i’s was not convincingly one of them. Latent mining the UK national database for men with ED not taking PDE5i’s in order to round out the investigative study comparator data simply yielded older and less healthy males within that subgroup.

Edited March 18 by SirBillybob

[Nightowl]

I got an Rx from my doctor and along with it came a coupon that cut the price for 13 25mg tablets down from $240 to $46.  I’m hoping I can use the same coupon for refills….