Mounjaro

[sydneyboy]

There has been quite a bit of discussion about weight loss medications here but I would like to confine the discussion to Mounjaro. I am seeking to lose about 15kgs and my doctor is prepared to prescribe it. I would be interested to hear from people who have taken this medication and what was their experience.

[Rohit]

What’s your BMI? For most people it works well, a few side effects are common such as indigestion and nausea. The dose is usually titrated up every month if needed. Tolerated it well, and have remained on 5mg as happy with weight loss and side effect profile 

[sydneyboy]

34 minutes ago, Rohit said:

What’s your BMI? For most people it works well, a few side effects are common such as indigestion and nausea. The dose is usually titrated up every month if needed. Tolerated it well, and have remained on 5mg as happy with weight loss and side effect profile 

My BMI is about 31-32. Thank you for your comment.

[+ Lucky]

I switched from Ozempic to Mounjaro and think that Mounjaro is the better choice. Yes, I lost weight on Ozempic, but didn't lost any of my cravings, specifically Häagen-Dazs® chocolate ice cream

With Mounjaro I have no interest in HD chocolate ice cream, but keep my attraction to chocolate milk. Fairlife chocolate milk has 12g sugar v. most chocolate milks 1t 28gm.

So it's an improvement, but I would also like to reduce that craving. My appetite is hardy, especially in the mornings.

Nonetheless, I am down about 60 pounds on the two drugs.

[LookingAround]

I'm on it. 15 mg and doing quite well. Essentially no side effects and similar to Ozempic. I am continuing on the weight loss program and just as with Ozempic I have lost any interest in alcohol. (I never had a problem with alcohol) I find it a great medication and I have no problems

[Danny-Darko]

On 10/16/2025 at 2:09 AM, Rohit said:

What’s your BMI? For most people it works well, a few side effects are common such as indigestion and nausea. The dose is usually titrated up every month if needed. Tolerated it well, and have remained on 5mg as happy with weight loss and side effect profile 

Sounds just like the initial adjustment period of Ozempic.

[sydneyboy]

Thank you all for your comments. Much appreciated. One question. How long did it take for you to get discernible results?

[LookingAround]

For me steady weight loss like a pound or two a week steady like a linear slope down and down and down over a couple of years. 

[Nebost]

I just started it less than a month ago, very pleased so far  lost 4 lbs, no side effects my BMI is 26.  In the US I believe Eli Lilly brands it  Zepbound if used for weight loss, Mounjaro if for diabetes and other ailments.  .  There are a bunch of sellers that sell compounded tirzeptide not sure of the efficacy or safety of that, so I went official product Eli Lilly product Zepbound (again, same as Mounjaro).

Edited October 18 by Nebost

[+ sniper]

I'm on Zepbound, which is the same drug as Mounjaro. For starters, i had about triple the weight to lose that you do, so it's possible the dose relative to weight plays a role. For the first couple of weeks my hunger signal COMPLETELY turned off. I think I could have gone three days without any calories and not been bothered. Frist week dropped 10 lbs then it went much slower after that.

One thing to be aware of is muscle loss. Since I go to the gym nearly every single day I didn't initially notice this. But recently I for scheduling reasons ended up not lifting(but still doing cardio).for a week and I feel like I had a much steeper dropoff in strength than I expected.

A colleague who was taking it for prediabetes issues and was not actually overweight at all was absolutely miserable on it. He had to work from home for the first month because he couldn't be away from a toilet for the length of his commute. So ymmv.

Edited October 18 by sniper

[+ sniper]

2 hours ago, Nebost said:

I just started it less than a month ago, very pleased so far  lost 4 lbs, no side effects my BMI is 26.  In the US I believe Eli Lilly brands it  Zepbound if used for weight loss, Mounjaro if for diabetes and other ailments.  .  There are a bunch of sellers that sell compounded tirzeptide not sure of the efficacy or safety of that, so I went official product Eli Lilly product Zepbound (again, same as Mounjaro).

My doctor specifically only sends his self-pay patients to Lilly because the compounding pharmacies aren't really regulated. That's not to say there aren't good ones, just that his office didn't feel they were in a position to assess and didn't want the risk.

[Nebost]

No bad side effects for me whatsoever, and only a moderate decrease in appetite .  My first month was 2.5 mg, but I’m increasing it to 5mg since the 1st month went so well. I work out 3 times a week, haven’t noticed any difference.  Maybe my sleep is better now?  Again, It’s only been a month.

My provider is Ro (the one that Serena Williams pitches for).  They charge me $645/month (145 for membership, 500 for the Zepbound).  I also didn’t want to risk the compounded semiglutides, they are much cheaper , and maybe they’re good but what you get really sick?

Edited October 18 by Nebost

[DenverDad]

Been on Mounjaro since April for diabetes management.  I started with 2.5 then 5.0 a month later then 7.5 a month after that.  My A1C went from 11.1 to 6.4 in about 2 months and I've lost 25 pounds since I've started (between the med and improved diet).  All my side effects have been gastro related (sulpher burps, constipation) but all have been manageable with OTC meds and increasing my fiber and water intake.  I've definitely noticed the decrease in food noise (constantly thinking about food) and decrease in appetite and cravings.  For me, the improvement in my blood sugar alone has been a game changer and a life saver.

PM if you have any questions.

[BigDMike]

I had starting Mounjaro back in AUG 2022 when you just needed a telehealth doctor to prescribe it and it was $25/month with a coupon.  That lasted for a good 2 or so years and then it started to get difficult in 2024 when it exploded and everyone was on it...get prescriptions filled was nearly impossible.  I started at 2.5 and went to 15.  I have lost 37 pounds in total.  When it started to get hard to get, I tried Ozempic...that last 3 months...my weight went back up and I was craving food so I gave up and went back to Zepbound as that was easier that Mounjaro at the time to get.  Earlier this year, that too started getting impossible to find locally and I was missing doses so I switched to a compound version from a local doctors med spa/health clinic.  I am back to 15 MG and while I am no longer losing weight, I am back down to my lowest weight and maintaining.  I have not had the side effects others have professed.  

[+ purplekow]

My brother a diabetic who needed to lose weight was fine until 7.5 and then the shit hit the fan and everywhere else.  He could not leave his house for more than two weeks and he was off the medication for another month.  In that time he regained the 30 pounds he had lost. He restarted at 2.5 and is now on 5 mg.  He does not intend to go higher as his HgbA1C is under 6.7 and he has not had a recurrence of the diarrhea.  He has lost about 50 pounds off of a 270 pound frame over the last 7 months.  To be totally open about it, in that same time he was diagnosed with lung cancer, had curative surgery but he has been unable to exercise to any extent, so his weight loss is strictly due to diet changes.  His lack of recovery of muscle tone after the surgery could be due to the medication.  

[+ sniper]

If I skip lifting weights for multiple days in a row, I definitely fall off faster strengthwise than I used to.