I used to get stuffy nose, headaches and heart burn everytime I took Viagra/Cialis.
Now, I take Pepcid 20 mg, Motrin 400 mg and 2 sprays of Afrin at the same timeI take either Viagra/Cialis.
That has eliminated my side effects 100%. Of course, YMMV.
Prilosec/Nexium should work as well as Pepcid...but seems like overkill to me.