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Everything posted by SirBillybob
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Right, the mid20teens Phase 2 study results provide clues to the Phase 3 results media release emphasis on zoliflodacin’s noninferior urogenital infection cure rate. All subjects had urogenital infection as it was the inclusion criterion. As in Phase 2, the recent trial cure rates for simultaneous pharyngeal or rectal infection were evaluated and compared to standard treatment. If noninferiority criteria had been met for either of those secondary outcome infection sites, albeit sufficiently statistically powered (unlike Phase 2), I assume it would have been enthusiastically mentioned. On top of that, there is the high cure rate requirement gold standard of 95% which was probably not satisfied for pharyngeal infection treatment with zoliflodacin if consistent with Phase 2 trends, even though Phase 3 dosing was the more effective higher dose of Phase 2 dose escalation. We will have to wait for the data to be peer reviewed but it appears to be more promising for Adam & Eve than for Adam & Yves. The former also benefit from the more overt symptom presentation of urethral and cervical gonorrhea whereas pharyngeal and rectal infection is usually detected, latently if at all, via routine screening.
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Having masseur finish on your body or face
+ SirBillybob replied to sammc's topic in Spas & Masseurs
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I would only need him to understand ‘ixnay hombre’.
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First time? Can relate. Fist time? Cannot.
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I thought it was powerful and moving. Second time hearing DiDonato, previous time was her Virginia Wolff role. I love her voice, so awesome particularly given her diminutive size. The theatre experience bringing in close-ups (not the staged filming) zoomed in visually a lot of the acting right down to perspiration and tears. The chemistry between Sister Helen and Joe, and with Sister Rose, spot on. The mother sang the original Helen role decades ago. The ritual of the alcohol swab alone, medically superfluous, so chilling.
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From London, Ontario. 17 pages of gossip about him at LPSG spanning 2 years. Apparently the OF account is quite tame and much of it is PPV above the subscription.
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We seniors all had chickenpox; very few evaded it and the four of you were a household Petri dish. It is highly unlikely she caught chickenpox as a senior from one of the 400 or so Canadians currently getting it each year. Yes, a reactivation such that both clinical entities present simultaneously is certainly rare, more common among older folks with co-morbidity (eg, diabetes).
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Though structure any dairy intake a few hours before or after popping the pill.
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Oral lead-in dosing might have been appropriate. https://medinfo.gsk.com/5f95dbd7-245e-4e65-9f36-1a99e28e5bba/e28f393c-fec0-4746-bd45-df61388fe935/e28f393c-fec0-4746-bd45-df61388fe935_viewable_rendition__v.pdf?medcommid=MED--US-9176#:~:text=When used for oral lead,directly to the initiation injections.
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Recapture what was lost... and blah blah blah...
+ SirBillybob replied to soloyo215's topic in The Deli
The platform being German let the usually restricted images thru as they seemingly represent an homage to “99 Luftballons”? -
Ah, I see. I guess I see the reviews because I am also outside of USA.
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What is the difference between a review and a “review narrative”? One can see the reviews already. Is there another tier, more elaborate, that is kept hidden within the platform?
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Mailing a letter to a providers residence
+ SirBillybob replied to Anthony's topic in Questions About Hiring
Good point. -
Mailing a letter to a providers residence
+ SirBillybob replied to Anthony's topic in Questions About Hiring
Try intercepting the provider at the local post office you have in common, where he daily inquires about undelivered fan mail. Seriously though, I wonder if you mentioned your geographic proximity in your initial communication, and how convenient that is etc, thus rendering him hesitant. -
It’s screening at a cinema near my home next Saturday, about $20USD. The chain is Cineplex (Canadian), where I also saw The Hours a while back.
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Postponed again. Likely May 2025.
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I did not write that sentence, so I don’t know how the quote could be mine. However, at this point, only the current updated Pfizer, Moderna, and Novavax vaccines are legit going forward. A bivalent booster administered earlier thIs year may offer some protection in the meantime as the updated versions relate to coronavirus descending from the Omicron family tree. It stands to reason that anybody waiting for the new vaccine but has not received a bivalent dose in a long time, example 9 months, should perhaps exercise greater exposure caution within the current landscape. That said, I personally know two people in their 70s that came down with COVID this summer not long after having had bivalent booster doses; one had a pricey bucket-list holiday ruined due to symptoms like a bad cold, and the other had quite a debilitating course in spite of Paxlovid uptake at the recommended stage. Actually, an updated vaccine can be used as a primary 2-dose series (prime + boost) for those never vaccinated, as was also the case for those that had never been vaccinated at the time the bivalent doses emerged about a year ago.
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Say goodbye to the COVID-19 vaccination card. The CDC has stopped printing them - Bowen Island Undercurrent WWW.BOWENISLANDUNDERCURRENT.COM It's the end of an era for a once-critical pandemic document: The ubiquitous white COVID-19 vaccination cards are...
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donation requested for viewing private gallery?
+ SirBillybob replied to + RyanDean's topic in Questions About Hiring
Homerotica. That tracks. -
donation requested for viewing private gallery?
+ SirBillybob replied to + RyanDean's topic in Questions About Hiring
Where the models are for viewing and speed-adjusted blowing occurs upon delivery. But dang those shipping charges. -
Ah, I took it that you had a typical household exposure more recent than a few weeks ago, or you thought you may have. With the allergies and all, and in that you likely go about your business when your home is serviced, less concern after all. He likely caught it some time following his last visit.
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This changes things because you now added that you have symptoms. Therefore, it is advisable from a public health point of view to behave as though you are infected until you rule out non-infection with either further rapid antigen testing because you may have two false negative results so far, or the more reliable lab-based molecular test (ie, RT-PCR) done at a facility. The assumption alone that you have SARS-CoV-2 without confirmation would be fine unless you are a candidate for the updated vaccination (I assume you are) because you could skip such a dose if you determine you actually are infected and will benefit from natural immunity. Personally, I would pursue the RT-PCR test to assist with vaccination decision-making. If it were Spring 2023, no later than early Summer, I wouldn’t make the suggestion.
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I cannot know for sure what member of the Omicron variant family tree I caught a month ago but the original generation of self-administered rapid tests showed positive, unsurprising due to symptoms.
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