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SirBillybob

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Everything posted by SirBillybob

  1. Resting and rising how many times?
  2. Now every word including the Lone Star state capital is an Omen.
  3. They’re off the privates in the privates.
  4. Context needed, although nothing can justify a racist put-down, not even hypothetical provocative shade hurled at an escort seeking friendship, such as: “Oh yeah? Well you’re just a low-level B-list porn star, which in fact just makes you an oxymoron!”
  5. I’d say I’m curious as well but I’m also right up to date.
  6. But throw in the air freshener for free?
  7. The idea is that two things can be simultaneously bad and are to be discouraged: prostitution and equivalency of culpability. Selling is considered to be wrong yet not subject to punitive legal consequences. In our strip club content context the net result is abolitionist-lite but correct awareness of the legalities in Canada may have relevance in general.
  8. Simply put, purchasing sex is illegal as of 2014. Prior to that only communication for the purposes of prostitution was an offence. The 2013 Supreme Court ruling only decriminalized sex workers’ selling of sex, prompting the new legislation that aligns with the Nordic Model. So yes, dancers do what they please with formal impunity, in contrast to customers. The door remains open for an exploitive consumer to face retribution, but that would be likely related to the abuse of a woman or child. It’s just that enforcement in strip clubs is little to none. The Montreal police have come into Campus as part of patrolling all commercial venues in The Village, essentially in the interests of community relations. They graciously refrain from entering the lap dance area, obviously aware of what’s up, and the club staff don’t rush into the area to urge the putting away of genitals. The clubs are perceived as a step removed and do not overtly directly profit from dancers’ earnings. https://www.justice.gc.ca/eng/rp-pr/other-autre/c36faq/c36faq_eng.pdf
  9. Good to know HenryHen isn’t a Henny Penny doom sitch. Wonder if cluckolding is a subspecialty.
  10. “You’re the best looking guy on the ad site. Too bad I’m male. Ph 555-555-5555”
  11. He was on an American reality TV show within the past decade, at age 41, the series now streaming on one of the major subscription platforms. What one could hire him to do currently is a ‘sticking point’.
  12. I take in outdoor stage events most summers. A broad range of offerings that deviate from the jazz genre in a traditional sense. Bear in mind that Canada Border Services staff are in a strike position. You can Google “CBSA strike” to keep up with developments. They are obligated to work but could do so ‘to rule’, slowing down entry at geographical borders and airports, etc. There are two fireworks events that happen to fall within the festival dates. You can watch them by walking a few blocks south on Papineau in The Village towards the bridge.
  13. That’s what I am coming up with basically as well for UK. If you didn’t already reach out to them, It may be a long shot because Lloyds liquidated this year but Lloyds Online Doctor may still exist as a separate entity. It is incorporated as a separate name: Expert Health Limited. The page on HPV stipulated, albeit ambiguously, that older males (>45) at risk could access Gardasil9 off-label and outside the NHS plan. The lead clinicians seem to be physicians with sexual health focus. Example: Dr Kieran Seyan. Gardasil is depicted as ‘out of stock’ but that may be due to the retail pharmacy chain’s closure status. Here’s the number. You might see if it is active and get a lead. I am not sure I would use the online consultation option before first determining by phone if it still exists.
  14. At this point, consensus is lacking, although early in the outbreak the Canadian guidelines included authorization for a 2-year booster dose following summer of 2022 primary series of two doses, if infection risk still applied. But then that provision was de-emphasized a few months later, seemingly in the context of worries about limited supply and, well, it appeared the incidence curve was flattening and it was impossible to predict the state of affairs for 2 years forward, but here we are. That said, there is no strong indication of a secondary wave at present that would trigger the need for a booster dose. The likely priority if a repeat outbreak occurs would be vaccination for a majority of the at-risk population with no doses obtained; and a 2nd dose for single-dose recipients to enhance herd coverage at the higher level of immunogenicity, clearly a substantial minority of those having receiving any MVA-BN; followed by considerations of a booster dose particularly for those that received one or two fractioned intradermal doses in their primary series. If you are engaging in a high-risk sexual network microcosm where Mpox is less contained, even if case incidence is low within the total population, it wouid be more important to consider the additional dose if you could access it.
  15. I had also been Vaccinia-experienced (Smallpox vaccinated), long before your travel-related uptake, and chose to receive only the single dose of MVA-BN some 24 months ago although I had access to the booster, administered subQ, if so desired. Along with the historical residual protection concept was the existence of evidence at the time suggesting that a delayed 2nd dose of MVA-BN yielded a stronger immunogenic response. Currently a very detailed paper has come out supporting the idea that a 2nd dose taken at this time two years on, obviously depending on whether a new incidence wave emerges, is actually better than having followed the initial recommended two-dose regimen. The single- vs two-dose efficacy difference at the current two-year point is not enormous because antibody decay following the second dose is more rapid. The above may be an important consideration for those MVA-BN-naive and considering vaccination uptake with or without the re-emergence of problematic new incidence. Interestingly, for those spared infection to date due to lack of pathogen exposure, two doses in 2022 appears to be less beneficial and to have been somewhat superfluous compared to an as yet delayed second dose, the benefit equivalence of which may justify a third upcoming dose some 23 months following second dose. I am still holding off on the second MVA-BN dose, balanced delicately against prospective case incidence patterns. D below is efficacy trajectory projected over a decade of time; shading is confidence interval. A, B, C are immunogenicity graphs with y axis demarcation gaps depicted on a log scale 0, 10, 100, 1,000.
  16. Off topic, but I just discovered Tubi for older Nick Galitzine films. Seems to be a free supplement to Apple. He is a co-lead in Handsome Devil playing a student and Andrew Scott plays a secondary role as a teacher. (I just edited out some adjectives due to their plot-spoiler status.😉)
  17. There would be no way to tease out that type of transmission risk in research because it is so specific and most occurrence of one partner’s semen on another’s skin wouid occur in the context of more extensive touching. However, HPV is essentially a skin infection and any concerns about HPV shedding in seminal fluid seem oriented to reproduction, for example, integrity of sperm. Personally, I would not be concerned about a guy’s splooge landing on “neutral” zones of my body. I might be more concerned about contact transfer: his hand on my genital area including scrotum if he had already been handling his own genital area. That said, GARDASIL vaccination is, at most, moderately protective in males and background HPV rates are considerably higher among MSM. Therefore, vaccinated MSM as a whole stand to acquire breakthrough infection and complications requiring medical attention at rates higher than infection among non-vaccinated non-MSM. That itself simply supports the value of vaccination. Mutual masturbation as you described, with risk front of mind, should be no less effective as a behavioural measure compared to more involved sexual activity in which some degree of false security may occur following vaccination.
  18. I tuned in to the first episode immediately upon release, as I often do for determining whether a show goes to watch-or-pass, and ended up binging the series. The final scene is rich. Emmy buzz occurring; nominations in two months.
  19. As long as he accepts cheeks bouncing on him.
  20. Just temporary signage as negotiated with the movie production company, among other external set alterations. Subbing for 1987 San Diego Gaslamp Quarter.
  21. Disappointing. Yes it does appear after all that UK is stricter in its off-label licensing flexibility. In Canada, there is provision for risk that is equivalent to that of GBMSM under age 46, and that equivalency applies to any man’s age. In Quebec, if not nationwide, male seniors can book Gardasil9 online with a pharmacy and pharmacists are authorized to administer without a physician’s prescription; of course paying out of pocket. In UK it appears that risk equivalency assessment is discretionary for certain subgroups, eg sex workers, but still capped at age 45. At first glance, the guidance language seems more flexible because it stratifies according to NHS covered cost. I thought the implication was age leeway for those willing to pay. That said, I am not entirely convinced that nobody older has accessed it and all I can recommend is to investigate MSM-user-friendly sexual health programs (I remain unclear as to the status of the clinic you refer to) to discover how much legal professional liability a clinician undertakes for providing vaccination that is deemed harmless for older age cohorts but simply less impactful on HPV population incidence. WHO has not taken a stance on HPV vaccination for older folks. This may be partly due to emphasis on capturing young groups worldwide and ensuring adequate supply when there have been, in fact, shortages historically.
  22. The conference paper indicates that Bexsero risk reduction dropped from 22% to 16% when analyzing cumulative GC infections, that is, new recurrences as opposed to first infection exclusively. There has been some chatter that a large Bexsero trial has since been cancelled but I have not been able to figure out if that relates to the ongoing large U Alabama study, the smaller Australian study, or a proposal not yet formally registered. I think that a viable vaccine is not on the proximal horizon. That said, the revised DoxyPEP analysis excluded a second set of analyses incorporating recurrences; the total incidence appears to add about 25% more cases to first infection incidence. My sense is that GC risk reduction will have dropped from the revised 33% to a less meaningful degree, particularly since the proportional hazards curves eventually intersect following a parallel rather than widening gap. If this omission was intentional, disingenuous even, perhaps it is moot given that I doubt any forthcoming DoxyPEP product monograph will include indication for GC prophylaxis. I think you mean Ceftriaxone with possibly Azithromycin or Doxycycline added for standard GC treatment. —- This brings us to recent data on standard Ceftriaxone effectiveness embedded in Innoviva’s Zoliflodacin noninferiority trial (mentioned in an earlier thread) and now GSK’s Gepotidacin noninferiority trial. The two new oral formulations and current standard treatment are showing around 90% cure rates, and these first-in-class developments are being framed as exciting. Well, no. It’s not a good time to acquire gonorrhea infection.
  23. Re: thread merging. Thanks for inserting the year-old topic. I had been aware of it. I consciously started the new topic as it is specific to the one bacterial STI [gonorrhea] most concerning for its increasing standard treatment failure rate, as well as adds vaccination concepts (eg, Bexsero) not included in the previous discussion but that had been referenced in at least one other thread on the board. Moreover, the previous topic discussion is antimicrobial resistance focused and requires unpacking the merits and liabilities of DoxyPEP alone across a broader range of viral and bacterial diseases. There are also several separate threads more relevant to gonorrhea alone over the past year, including vaccination as mentioned, newly emerging first-in-class oral treatment medications, and acute disseminated gonococcal disease. Anybody wishing a more integrative reading experience is advised to use the search term ‘gonorrhea’ on the board.
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