BCMan Posted June 19 Posted June 19 (edited) The Food and Drug Administration on Wednesday (6/18) approved a powerful new prevention drug for HIV called Yeztugo that promises to keep most people virus-free with two shots a year. (Wall Street Journal) Edited June 19 by BCMan Adding source Whippoorwill, marylander1940, Dolman and 1 other 1 3
BCMan Posted June 19 Author Posted June 19 (edited) Yeztugo has an annual list price of $28,218 in the U.S., which Gilead said was in line with existing branded PrEP options. The company said it is working to ensure broad insurance coverage for the drug, and to help defray any out-of-pocket costs. (Wall Street Journal) Edited June 19 by BCMan Nightowl, + Pensant and marylander1940 3
Danny-Darko Posted June 19 Posted June 19 FDA approves Gilead's twice-yearly HIV prevention injection, offering a powerful and convenient new option WWW.CNBC.COM The launch of the injection faces potential threats, including the Trump administration's proposed cuts to federal... marylander1940 1
Guest Posted June 19 Posted June 19 Isn't this functionally similar to a vaccine? You could theoretically eliminate the virus spread in one generation if everyone gets on it and it is made extremely accessible/cheap. But these demons will most certainly milk this epidemic for a few more years.
+ sniper Posted June 20 Posted June 20 On 6/18/2025 at 8:45 PM, BCMan said: Yeztugo has an annual list price of $28,218 in the U.S., which Gilead said was in line with existing branded PrEP options. The company said it is working to ensure broad insurance coverage for the drug, and to help defray any out-of-pocket costs. (Wall Street Journal) The only reason anyone is paying for branded PreP options is pharmacy benefit managers. It should be a scandal but I guess there are too many people with their hands in the cookie jar.
+ BenjaminNicholas Posted June 20 Posted June 20 This is an injection I won't likely be getting. Most providers will want to inject it into the abdomen and it's a rather large dosage of liquid. My own ID doc said that it's likely it will remain visible on the stomach for some time, either as a pouch of liquid or a slightly raised plateau. + claym, marylander1940, + Pensant and 2 others 1 3 1
Guest Posted June 20 Posted June 20 4 hours ago, BenjaminNicholas said: This is an injection I won't likely be getting. Most providers will want to inject it into the abdomen and it's a rather large dosage of liquid. My own ID doc said that it's likely it will remain visible on the stomach for some time, either as a pouch of liquid or a slightly raised plateau. Don't you feel like it's a small price to pay? Especially if this injection does not have the horrible renal side effects of Prep? Personally speaking, those side effects are the main reason why I am choosing to adjust my life to prep on-demand so I welcome this invention if it is more bearable on my body.
+ BenjaminNicholas Posted June 20 Posted June 20 6 hours ago, Felange said: Don't you feel like it's a small price to pay? Especially if this injection does not have the horrible renal side effects of Prep? Personally speaking, those side effects are the main reason why I am choosing to adjust my life to prep on-demand so I welcome this invention if it is more bearable on my body. For me, I've been on some form of PrEP since Truvada trials in late 2010. I get bloodwork every 90 days. My renal numbers have remained perfect. The talked about side-effects aren't widespread and are highly overdramatized. The rough percentage of those who have any renal issue is 2.3% + Pensant, + Vegas_Millennial, + claym and 1 other 2 2
Guest Posted June 20 Posted June 20 4 minutes ago, BenjaminNicholas said: For me, I've been on some form of PrEP since Truvada trials in late 2010. I get bloodwork every 90 days. My renal numbers have remained perfect. The talked about side-effects aren't widespread and are highly overdramatized. The rough percentage of those who have any renal issue is 2.3% Yeah it's probably worse in my head also. I always assume the worst unfortunately. Thanks for the feedback.
+ sniper Posted June 20 Posted June 20 I feel like with a shot there's more risk it wears off for some sooner than others, people drag their feet and go more.than 6 months, etc. Then again lots of people are terrible about taking daily pills too I suppose.
+ sniper Posted June 20 Posted June 20 12 hours ago, BenjaminNicholas said: This is an injection I won't likely be getting. Most providers will want to inject it into the abdomen and it's a rather large dosage of liquid. My own ID doc said that it's likely it will remain visible on the stomach for some time, either as a pouch of liquid or a slightly raised plateau. So you're saying it's PreP for bears? + BenjaminNicholas, Whippoorwill and + Pensant 3
+ Gar1eth Posted December 6 Posted December 6 Anyone thinking about using it? https://www.webmd.com/drugs/updates/fda-approves-first-twice-yearly-shot-to-prevent-hiv?ecd=socpd_fb_Gen_1624_spns_ctv92705_conmkt&fbclid=IwZXh0bgNhZW0BMABhZGlkAasl9G8GRfxzcnRjBmFwcF9pZAo2NjI4NTY4Mzc5AAEep98Mn6owAV3BoVYB0wI1Fztwrcbs9pmqRdRc7aVlCoyAH5F68HhFAw_VQII_aem_jHpj7pF27i66sSwDCJh7tw&utm_medium=paid&utm_source=fb&utm_id=120231546745910156&utm_content=120231546746040156&utm_term=120231546745950156&utm_campaign=120231546745910156
LookingAround Posted December 6 Posted December 6 Yes but my insurance wouldn't approve it unless I had failed Apretude which I hadn't.
+ Gar1eth Posted December 7 Posted December 7 2 hours ago, LookingAround said: Yes but my insurance wouldn't approve it unless I had failed Apretude which I hadn't. How would you fail it? If you ended up getting HIV, you wouldn't be eligible for it.
LookingAround Posted December 7 Posted December 7 2 hours ago, Gar1eth said: How would you fail it? If you ended up getting HIV, you wouldn't be eligible for it. Side effects. + Gar1eth 1
+ Gar1eth Posted December 7 Posted December 7 7 hours ago, LookingAround said: Yes but my insurance wouldn't approve it unless I had failed Apretude which I hadn't. 4 hours ago, Gar1eth said: How would you fail it? If you ended up getting HIV, you wouldn't be eligible for it. 2 hours ago, LookingAround said: Side effects. My Magic Eight Ball says there's a very good chance you are going to get extremely nauseous -not to mention sore at the injection site -from your next Apretude injection. LookingAround 1
+ Vegas_Millennial Posted December 7 Posted December 7 (edited) On 12/6/2025 at 11:35 AM, Gar1eth said: Anyone thinking about using it? Existing discussion in the Men's Health section: Plus, a new trial for once a year injections: https://www.companyofmen.org/topic/164922-consider-gilead’s-new-us-based-prep-trial/?do=getNewComment Edited December 7 by Vegas_Millennial marylander1940 1
+ Gar1eth Posted December 7 Posted December 7 51 minutes ago, Vegas_Millennial said: Existing discussion in the Men's Health section: Plus, a new trial for once a year injections: https://www.companyofmen.org/topic/164922-consider-gilead’s-new-us-based-prep-trial/?do=getNewComment Thanks I thought I had looked there. Apparently I missed it. + Vegas_Millennial 1
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