FreshFluff

I looked into this and was not overly impressed. The idea is that their false posirive rate is low, but the downside is, of course, a relatively low sensitivity (true positive rate) for stage 1 cancers. From their press release, https://grail.com/press-releases/grail-announces-positive-new-data-with-multi-cancer-early-detection-blood-test-from-ccga-study/ “Detection rates (sensitivity) for the 12 deadly cancer types ranged from 59 to 86 percent at early stages (stages I-III). A combined analysis of this group of cancers showed robust detection at early stages (34 percent, 77 percent, and 84 percent at stages I, II, and III, respectively). In addition, a tissue of origin result was provided for 94 percent of all cancers detected and, of these, the test correctly identified the tissue of origin in 90 percent of cases. The 12 pre-specified cancer types included anorectal, colorectal, esophageal, gastric, head and neck, hormone receptor negative breast, liver, lung, ovarian, and pancreatic cancers, as well as multiple myeloma and lymphoid neoplasms. Together, these cancer types account for approximately 63 percent of all cancer deaths in the United States.” First of all, is stage 3 considered “early stage?” And how do they work up the positive results? With a full body PET scan or what? Also, I\they’re not breaking down the sensitivity rates by stage for each type of cancer. If the test’s sensitivities for, say, ovarian and breast are far higher than the rest, then—assuming you’re male—you’re wasting your time. From my lay perspective, it might or might not be worth signing up for the trial based on the current data they’ve submitted. After the results come back, you might need a lot of patience and tolerance for “we have no clue what’s going on”-type responses.

I’m old enough to remember when “automatic transmission” didn’t make me think of COVID.

-International calls placed by an operator -Duck and cover drills in school, though we were told they were for earthquakes -The TV movie The Day After

I’m glad to hear that you’re well.

That was before we knew about long COVID. The people I know who have gotten infected in the past few weeks (with BA5?), all first timers, are sicker than anyone expected. They’re still experiencing fatigue 4 weeks later. I very much hope that hope they are not affected long term. I’m going masked in crowded indoor settings and dining out outdoors only. I doubt it will be enough.

Yeah, you got yours, biiiiiitches! Oh, wait. That was me.

Thanks for posting this. I haven’t been but have always been curious about the island’s history. This book will be on my Kindle soon.

Have you found yourself wanting to have sex with those people though? 😉

I joined just after Trixie left. I always enjoyed reading his posts about picking up trade. His scouting missions to the Tenderloin in SF were particularly controversial.

PM’d you, @Coolwave35.

Welcome to the CoM, @KateNickolson.

OP said he the son was visiting from out of town. Is he in college? If so, I would avoid any comments that include the word “sexy.” Remember that the neighbors still think of him as a kid. All this assumes that the son is an adult over 18.

The answer to this type of question is usually, “If you have to ask, the answer is no.” But if I were a betting kitten, I’d put $100 on “yes.” Are you hot?

When you put in the effort to look adorable while singing the school’s alma mater at your reunion

Happy birthday, Honcho! You’re one of the sweetest members on this forum, and I always look out for your posts.

I’m having a tough time imagining a hidebound traditionalist like Prince Charles starting a new tradition.

I keep imagining my reunion as narrated by Tom Wolfe.

Happy birthday to RadioRob. This community exists today because he stepped in and took action.

We will all miss her open, welcoming nature and her intelligence. RIP.

Oh my God. I thought she was doing ok. I messaged her a hear ago and was going to contact her again.

I'm glad you got a chance to talk your favorite professor that he had made a difference in your life. I wanted to do the same with a middle school teacher. I contacted the school, who's representative tried without success to contact her. As for the professor who took advantage of you, I'm really sorry.

I'm still here! https://getyarn.io/yarn-clip/7f34fab4-f215-4d2e-aaac-63b06d82db2a

I'm all gussied up and on my way over. My mood: https://www.instagram.com/tv/CeLI_VLoR4Q/?igshid=YmMyMTA2M2Y=

https://www.instagram.com/tv/Cd9kchSpJcR/?igshid=YmMyMTA2M2Y=

The price of regular was up to $7.29 as of a few days ago.