Any experience with Wegovy?

[marylander1940]

I'm amazed about how fast the obesity acceptance movement has almost disappeared now that there's a drug to lose weight without a commitment to changing a person's lifestyle, etc. 

[nomad]

It has definitely changed many people's lives with the simple impact of improving their self-confidence and how they look at themselves.  We are our worst critics.  

Edited June 15 by nomad

[marylander1940]

6 hours ago, nomad said:

It has definitely changed many people's lives with the simple impact of improving their self-confidence and who they look at themselves.  We are our worst critics.  

Eating healthier, walking daily and joining a gym can also change self-confidence. Obviously, an injection is a lot easier and effortless. 

I hope years from now nobody regrets this "shortcut" to losing weight

[nomad]

Agreed.  The long term side-effects are unknown.  A friend recently started using it and the change in her body confidence could not be more stark.  

[marylander1940]

On 6/15/2026 at 7:46 PM, nomad said:

Agreed.  The long term side-effects are unknown.  A friend recently started using it and the change in her body confidence could not be more stark.  

Did she try eating healthier, moving more, etc. before taking an injection/pill? Just wondering.

As much as I LOVE this country, I wonder why so many folks think taking a pill/injection is the only solution to all problems.

 

Edited June 17 by marylander1940

[nomad]

She did.  Exercised regularly and ate decently.  However, her metabolism is slower than normal.  The injection kind of turbo charged her results from exercising and eating better.  Whereas before, she wasn't always able to do both of things always at the same time so the results would be uneven.  

[nomad]

22 hours ago, marylander1940 said:

I wonder why so many folks think taking a pill/injection is the only solution to all problems.

Many are lazy and opt for the easier path.  We are a nation addicted to pills for the quick fix.  Whether it is vitamin supplements or Oxy or meth or Viagra or GLP-1s.  

[marylander1940]

8 hours ago, nomad said:

Many are lazy and opt for the easier path.  We are a nation addicted to pills for the quick fix.  Whether it is vitamin supplements or Oxy or meth or Viagra or GLP-1s.  

Instead of asking: "What can I do?" they ask the Dr: "What can I take?'

[BSR]

Obesity wasn’t a problem in 1970s America.  In 1970, only 14% of Americans were obese whereas today more than 42% are.  More worrisome, less than 5% of kids were obese in 1970, today more than 20%.  What changed?  The amount of sugar in food, the amount of processed and ultraprocessed food we eat, and yes, portion sizes.

Whereas sugar wasn’t a major ingredient in food in the 1970s, it’s packed into everything now:  soup, ketchup, salad dressing, protein bars, cereals, yogurt, you name it.  Prior to 1970, we ate very little ultraprocessed food; now, yikes!  Portion sizes are out of control.  The typical appetizer at Cheesecake Factory is definitely enough food for a person’s entire dinner, and the main courses can easily feed two (3? 4?)

Even if you reduce portion sizes and exercise more, you’ll still struggle to lose weight if you ignore the hidden sugar in food and/or eat a lot of ultraprocessed food.  Both will keep your insulin level high, which traps bodyfat so that you never burn it off.

[+ sniper]

We've engineered activity out of daily life to the point it's very hard for a fair portion of the population to keep their weight down. You exercise more and your basal metabolism drops because you are more efficient. But you are hungrier because you're spending more time at peak output.

There was a time in my life where I was 50 lbs overweight with a resting heart rate in the 50s. I was spending hours in the gym and then had to cut back because my joints were shot. But my desire for food did not drop back when my activitiy levels did and before I knew it I was 100 lbs overweight. I continually lost and gained the same 25 lbs for years and it was CONSTANT thinking about what I was eating what/when I could eat next whichever phase of the cycle I was in.. If you never actually get to that point I don't think you can really "get" what it feels like to have that food noise. I took my first shot and it just...stopped.

GLP1s are a fucking godsend and if you don't need them, just be grateful. The people I know on them are going to the gym too. And as the cost of the drugs come down I'm pretty confident it will pencil out with the savings on heart and kidney disease treatment. Since i started my bloodwork has been better than ever...EVERY number in the normal range, in some cases better than when I was the "proper" weight AND much younger. 

[+ purplekow]

Now ending clinical trials GLP 3 drugs are in the pipeline and are reported to have more associated weight loss and thusfar, fewer side effects.  As with other weight loss regimens of the past, Fen Phen anyone?, side effects are always a concern.  However, 4400 suits, some of them baseless no doubt, is a very small percentage compared to the number of people taking these drugs.  Though I am obese and I have been diligently going to the gym 3 days a week for weight training and at least 2 days a week for cardio for more than a year, my weight loss has been minimal though my body is fitter and I am more functional.  I have been watching my diet as well though not with severe calorie restriction.  Though my brother lost over 60 pounds in 6 months and my sister lost 40 pounds in the same time period, I have refrained from using any medication.  

My hesistation has to do with potential side effects. I do not hold the distain for people who are using these medications that other posters here have expressed as especially those with Type 2 diabetes may see dramatic improvement in their diabetic control along with their weight loss.  Their weight loss may also allow for exercise that they were previously limited in doing.  

[BigDMike]

3 hours ago, purplekow said:

Now ending clinical trials GLP 3 drugs are in the pipeline and are reported to have more associated weight loss and thusfar, fewer side effects.  As with other weight loss regimens of the past, Fen Phen anyone?, side effects are always a concern.  However, 4400 suits, some of them baseless no doubt, is a very small percentage compared to the number of people taking these drugs.  Though I am obese and I have been diligently going to the gym 3 days a week for weight training and at least 2 days a week for cardio for more than a year, my weight loss has been minimal though my body is fitter and I am more functional.  I have been watching my diet as well though not with severe calorie restriction.  Though my brother lost over 60 pounds in 6 months and my sister lost 40 pounds in the same time period, I have refrained from using any medication.  

My hesistation has to do with potential side effects. I do not hold the distain for people who are using these medications that other posters here have expressed as especially those with Type 2 diabetes may see dramatic improvement in their diabetic control along with their weight loss.  Their weight loss may also allow for exercise that they were previously limited in doing.  

Yep, GLP-3 are due next year....specifically Retatrutide is likely going to be the next big thing as they are in final stages now.  

I see your point and admittedly, the side effects are not same for everyone....but that's not to say you would have a worse experience than others.  

However, when I speak to people they are more concerned about necessity to stay on these drugs for an extremely long/extended period of time...if not forever.  This drug doesn't cure, change or re-engineer your body so that over time, you can go on without them and keep the weight off.  They are only as effective as when you take them...and if you do well, lose weight and then eventually go off the drugs....you would need to ( ie MUST) refrain what whatever put you in that initial place originally....whether that's food or exercise or other factors.  If you're on these and do well...WOOHOO....though if you are comfortable and stop taking them....it should not come as a surprise that weight will come back.  Of course anything is possible.....but more often than not...the end result is consistent amongst people taking them.

Edited Saturday at 08:25 PM by BigDMike

[+ purplekow]

1 hour ago, BigDMike said:

Yep, GLP-3 are due next year....specifically Retatrutide is likely going to be the next big thing as they are in final stages now.  

I see your point and admittedly, the side effects are not same for everyone....but that's not to say you would have a worse experience than others.  

However, when I speak to people they are more concerned about necessity to stay on these drugs for an extremely long/extended period of time...if not forever.  This drug doesn't cure, change or re-engineer your body so that over time, you can go on without them and keep the weight off.  They are only as effective as when you take them...and if you do well, lose weight and then eventually go off the drugs....you would need to ( ie MUST) refrain what whatever put you in that initial place originally....whether that's food or exercise or other factors.  If you're on these and do well...WOOHOO....though if you are comfortable and stop taking them....it should not come as a surprise that weight will come back.  Of course anything is possible.....but more often than not...the end result is consistent amongst people taking them.

These drugs which allow for weight loss are no different then other weight loss methods in that there is a rebound if you falter.  Essentially, our bodies are not designed to lose weight.  Gining weight is a guard against times of famine, which for most people in the US, is not a problem.  Thus, when you stop taking in calories, the body's response is to lower basal metabolic rate and keep it there.  Thus, if you go back to your previous behavior, the lowered metabolic rate now gives your body decreased calorie usage and though you are taking in the same number of caolires you were previoussly, the decreased uage allows for regaining of weight, usually above the previous level.  Yo-yo dieting is a fact of modern life due to this change in basal metabolic rate.  Usually, about two years will be needed to balance out basal metabolic rate and weight, so if you can keep the weight lost on a strict weight loss program, you have a reasonable chance of keeping the weight off.  But, two years is a long time and for every 100 calories of excess intake, there is a gain of one pound per month, approximately.  So if you slow your metabolic output down by 200 to 300 calories per day and then resume that same diet afterwards, you may expect to gain more than 30 pounds in a year while your body re-equilibrates.