20 years into my career the company I worked for went under. I was a wreck. The labor market in my area was tight and suddenly flooded with over 1000 newly unemployed individuals. My house was deeply under water so relocating was not an option. I did some consulting and volunteer work for a while as I assessed my situation.
One of my greatest fears was that my skill set was limited to the very specialized area of my last position. I decided to take a 90 degree turn and do something completely different. I took classes to develop the skills I needed as well as prove to myself that I had the ability to learn new skills.
I've worked in that industry for the past 14 years but seeing the writing on the wall (online businesses changing that industry) started looking for a new job.
It took 4 years and 100s of applications but am now 3 weeks into my 3rd major career.
The things that tipped the scales in my favor:
Work ethic
Community engagement
Strong references
Well built resume
I strongly urge you to speak with a job transition professional be it a resume consultant or head hunter. They often see the marketable skills the don't occur to you because it was 2nd nature to you. "Just part of the job."
Abilities like prioritization, multitasking, logistics, attention to detail, etc are so often automatic as to be overlooked and unrecognized by experienced workers.
And, finally, approach your job search as a job. Apply the skills you've developed and your work ethic to it as you did your recent career.
It's not easy, believe me I've been there. You'll send out dozens of applications/resumes with little response. It's the nature of the beast. Don't let it get to you too much. Your value will ultimately be recognized.