World-first gonorrhoea vaccine launched as infections soar!

[Danny-Darko]

Gonorrhoea vaccine to be rolled out in England from August

WWW.BBC.COM

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The treatment will be offered to those most at risk from August after a record number of cases.

 

[SirBillybob]

Further research is desperately needed. There is yet to occur a statistically significant prophylaxis effect within the gold standard methodology of randomized control trial. Differential effectiveness by anatomic site (urogenital, anal, pharyngeal) is unknown. Serological correlates of any true protection are yet to be identified. If you can qualify and spare the time for a trial that may be accessible geographically, and tolerate possible random assignment to placebo, you may be doing as much a worthwhile service as uptake of 2 vaccine doses alone. The tradeoff of infection due to non-vaxx control study arm assignment may be tolerable to you given the lack of impressive efficacy to date and the prospect of effective treatment upon infection in spite of growing antimicrobial resistance.  

ADDENDUM: Oops, apologies. No such ongoing or additional studies currently recruiting research subjects seem to exist.

The small challenge trial in North Carolina where subjects are assigned to vaccine or not and then clinically infected with gonorrhea, obviously with treatment backup contingencies, is progressing at a snail’s pace with results still years out.

Use, or supplement vaxx with, according to taste: 

Edited May 21 by SirBillybob

[SkyBliss]

I went and got the Uromune vaccine in the UK. Helps prevent UTIs caused by Escherichia coli, Klebsiella pneumoniae, Enterococcus faecalis, and Proteus vulgaris. 

However, I agree with @SirBillybob-  condoms are a great, and less expensive preventative measure.

[kingsley88]

For some reason I thought vaccines were for viruses? Isn't gonorrhea a bacteria?

[SirBillybob]

2 hours ago, kingsley88 said:

For some reason I thought vaccines were for viruses? Isn't gonorrhea a bacteria?

Perhaps because our most recent vaxx dances have been with viruses. Viruses and bacteria have in common surface proteins, ie, antigens. The 4CMenB vaccine produces antibodies that can recognize and neutralize gonococcal antigens.

Many of our routine childhood vaccinations confer prophylaxis against bacterial pathogens. My latest senior vaccine was for protection from bacterial pneumococcal disease. If I step on a rusty nail this summer my vaccine dose will not be virally based. 

Edited May 23 by SirBillybob