Oh, Wrigleyville is one of the many neighborhoods. Like I live Printers Row. There are tons of them but usually the "Side" is named first, unless you know that the person what neighborhood you will be referring to. For instance, someone might not necessarily know where "Boystown" or "Chinatown" or "Brownsville" or "Humboldt Park" or "Lincoln Park" is - (many are associated and named with the park that they contain, like "Jackson Park.") I think President O'bama is from Kenwood. Otherwise you would just say, "it's on the North Side" or "it's in the Loop."
P.S. I'm sure she has a enough money to buy one of the neighborhoods and just start having it called by her name. "Orpahville"