Hubby and I had a weekend seaside home full of antiques and art that we rented out by the week using Homeaway and VRBO. Over eight years, renting it out a few weeks each summer brought in over $100,000, with never a speck of trouble. Pricing it at $3600/week and taking a sizable security deposit may have helped screen out the riffraff. And having a housekeeper whom guests knew would be there to see them in, and again to see the place as they checked out.
Life can be a lot more enjoyable if you approach risk by realistically assessing and mitigating it, not straining to eliminate it at any cost. The gentleman in black with the formaldehyde pump will help us out with the latter only too soon.