I am legally blind and do most navigating on the internet via voice command rather than by physically typing, scrolling or dragging. The extra large (super-sized actually) font I use does help somewhat. So, some actions that others are able to do easily, and take for granted, sometimes become difficult for me. I never complain, though, as I do have some sight, while there are others whom I have met through the VA Low Vision office are completely blind.
But thank you for asking.