lukin4me78

Thanks - I needed this too! 

I haven't seen this conclusive research about only gay men. Don't most HIV medication studies work with populations of "persons living with HIV (PLWH)" whoever they might be -- men, women, straight, gay, trans, and bisexual?
Here's an example:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525920/

This does not happen by missing a single dose.  Almost all meds today have a 36 hour half life.  A person would have to not take the medicine for at least 2 days before they would see relevant development.  And it is not a delayed affect.  If they go for 3 days, the virus starts building.  
 
FYI on the U=U conversation - a person is considered transmissible at 200 copies per deciliter.  Most doctors start asking questions when a person tests above 50/dl.  Tests can pick up as little as 20/dl.  

This article from the Mayo Clinic is a fairly easy layman terms read:  https://newsnetwork.mayoclinic.org/discussion/forty-years-of-hiv-aids-will-the-epidemic-end/
"The reason why it is so difficult to cure HIV is that once HIV infects a person's body, it integrates into the host genome of several cell types. Those cells then hide in any of the lymphoid tissue, such as the lymph nodes, the liver and the spleen. And they lay there as what we call "latent" or "hiding", as long as the person is on HIV therapy. Anytime a virus does leave a cell, it gets taken care of by HIV therapy. But if the infected individual stops the HIV therapy, that latent virus will come back. To cure HIV, you have to eliminate those hiding viruses in the cells or that latent viral reservoir..."
 
There are two main reasons.  The first is this above, regarding the "hiding" capability of the virus.   Secondly, the virus' ability to mutate (or change its own form) rapidly means that targeting the virus itself is rather difficult.  Essentially - while there are two main forms of HIV (HIV-1 and HIV-2), those main groups have thousands of mutations.  Medicine can target certain markers that are similar, but even at that - the virus can mutate.  This is what people in the tread are talking about when they refer to resistance and why stopping medication "to give their body a break" is not a good idea.
Mutation rate is not really easy to make layman term-ed, but here's an article that makes a good attempt.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574155/
 
The best thing is that you are wanting to learn.   Please continue to educate yourself -- and keep asking questions!
 
HTH 

This article from the Mayo Clinic is a fairly easy layman terms read:  https://newsnetwork.mayoclinic.org/discussion/forty-years-of-hiv-aids-will-the-epidemic-end/
"The reason why it is so difficult to cure HIV is that once HIV infects a person's body, it integrates into the host genome of several cell types. Those cells then hide in any of the lymphoid tissue, such as the lymph nodes, the liver and the spleen. And they lay there as what we call "latent" or "hiding", as long as the person is on HIV therapy. Anytime a virus does leave a cell, it gets taken care of by HIV therapy. But if the infected individual stops the HIV therapy, that latent virus will come back. To cure HIV, you have to eliminate those hiding viruses in the cells or that latent viral reservoir..."
 
There are two main reasons.  The first is this above, regarding the "hiding" capability of the virus.   Secondly, the virus' ability to mutate (or change its own form) rapidly means that targeting the virus itself is rather difficult.  Essentially - while there are two main forms of HIV (HIV-1 and HIV-2), those main groups have thousands of mutations.  Medicine can target certain markers that are similar, but even at that - the virus can mutate.  This is what people in the tread are talking about when they refer to resistance and why stopping medication "to give their body a break" is not a good idea.
Mutation rate is not really easy to make layman term-ed, but here's an article that makes a good attempt.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574155/
 
The best thing is that you are wanting to learn.   Please continue to educate yourself -- and keep asking questions!
 
HTH 

This does not happen by missing a single dose.  Almost all meds today have a 36 hour half life.  A person would have to not take the medicine for at least 2 days before they would see relevant development.  And it is not a delayed affect.  If they go for 3 days, the virus starts building.  
 
FYI on the U=U conversation - a person is considered transmissible at 200 copies per deciliter.  Most doctors start asking questions when a person tests above 50/dl.  Tests can pick up as little as 20/dl.  

This article from the Mayo Clinic is a fairly easy layman terms read:  https://newsnetwork.mayoclinic.org/discussion/forty-years-of-hiv-aids-will-the-epidemic-end/
"The reason why it is so difficult to cure HIV is that once HIV infects a person's body, it integrates into the host genome of several cell types. Those cells then hide in any of the lymphoid tissue, such as the lymph nodes, the liver and the spleen. And they lay there as what we call "latent" or "hiding", as long as the person is on HIV therapy. Anytime a virus does leave a cell, it gets taken care of by HIV therapy. But if the infected individual stops the HIV therapy, that latent virus will come back. To cure HIV, you have to eliminate those hiding viruses in the cells or that latent viral reservoir..."
 
There are two main reasons.  The first is this above, regarding the "hiding" capability of the virus.   Secondly, the virus' ability to mutate (or change its own form) rapidly means that targeting the virus itself is rather difficult.  Essentially - while there are two main forms of HIV (HIV-1 and HIV-2), those main groups have thousands of mutations.  Medicine can target certain markers that are similar, but even at that - the virus can mutate.  This is what people in the tread are talking about when they refer to resistance and why stopping medication "to give their body a break" is not a good idea.
Mutation rate is not really easy to make layman term-ed, but here's an article that makes a good attempt.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574155/
 
The best thing is that you are wanting to learn.   Please continue to educate yourself -- and keep asking questions!
 
HTH 

Profile has been deleted now...   he was a good looking guy though...

Have seen his ad many times and am tempted myself.  Then I remember that every time I've hired a "straight boy" it has been a disappointment.  I desire someone who at least can act like he desires me, if only for an hour.  The other thing I've noticed is that Dallas prices are absurd.  Recently I've paid $300 for a massage and $400 for a rentboy session. I would not have ever paid these amounts had I not had some extra coin from tax season.  (And I was feeling more lonely than usual.)  But I can't really afford such prices, so I suppose I'll have to take a sabbatical.