Yes, the Mayflower folks were friendly at first, later they started the conquest of native land calling them the worshippers of Satan. Defensive wars, history repeats itself. The Spanish, Portuguese and the French at least practice mixed marriages. The English and Dutch would trade with them, and occasionally sign alliances putting one tribe against the other, but the main goal was removal, over and over again, something we practiced too combined with open biological warfare by G. Washington.
I guess now it's a good time for the aliens to come out and introduce themselves, a proposal for a Trump Tower in Mars would be enough to welcome them with open arms.